While our FGD showed that 86% of TPs were aware about CT and 14 % of them were unaware about CTs and 28.57% TPs were not aware who will sign for child who participated in CTs. This shows that overall public selleck products awareness about CTs was poor. Source of information about CTs: TPs got the information about CTs mainly from their physician (72%) and the other sources were friends and relatives (14% each). The main reason of participation in CTs: It was doctor’s advice (70%). The other reasons were the drug may be useful for curing their disease and just wanted to try it out (15% each). Attitude towards participation in CTs: 15% of TPs were not willing to participate in any study in future but thought that people should volunteer for the benefits of others while 15 % said they will participate even if their family member and close friends object.
The same percentage of people (15%) said that they will participate only if their family members have no objection. These participants pointed out that ??their family member’s opinion was valuable for them??. Remaining 55% said they will participate and they perceived that ??people should participate in CT??. 20% of NTPs stated that they will participate after discussing the risks involved with their family members. One NTP declared that he will decide to participate after discussing with others who had already participated in the study. 9% of NTPs thought that they will be doing favour to the doctor by participating in CTs. 80% of the NTPs were worried about the adverse events and therefore they had made a decision of not participating in a CT.
91% TPs were concerned about the compensation. They would participate only after getting assurance from the investigator. Only 9% each said that they will participate for a noble cause and advancement of science. Knowledge of Informed Consent Form: All the NTPs had no knowledge of Informed Consent Form (ICF). Among TPs, 85% of participant had signed the ICF while 15% were not aware Brefeldin_A of the term ICF and were unaware of what document they had signed. All of them said there must be transparency in the ICF and signing should be a must for all kind of studies. CTs experience: 15 % of TPs revealed that the overall CT experience was not very good. It was very time consuming and they had to travel far away distance. For 15 % of the participants, the experience was very painful and they had to withdraw from the trial.
While for (70%) of the respondents, the CTs experience was good. next They got free medicine, free check up and free transportation, their health status improved, they received more attention from the doctors, and furthermore they were satisfied with all study team members and said study team was co operative and helpful. Risk and Benefits of CTs: Among NTP 80 % felt that it is risky to participate in trial because drug is still in trial phase and at this stage, no one knows the side effects.