Uchiyama

I: Hierarchical clustering algorithm for compreh

Uchiyama

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M, Rupp R: Dendroscope: An interactive viewer for large phylogenetic trees. BMC Bioinforma 2007, 8:460.CrossRef Competing interest The authors declare that they have no competing interest. Authors’ contributions GHM performed computational analyses. BV, JMA and GHM were involved in conception and interpretation of the results and drafting the manuscript. BV, JMA and GHM were involved in critically revision the manuscript for intellectual content and approved the manuscript for publication. All authors read and approved the final manuscript.”
“Background Alanine-glyoxylate transaminase A vast array of bacteria, archaea, viruses and eukaryotes inhabit the tract of the human gut and form its microbiome [1, 2]. Investigation into the composition of this densely packed community and its effect on the host have revealed several benefits derived from the microorganisms such as plant polysaccharide processing and amino acid synthesis [1, 3]. The species structure of the community has also been linked to several health problems such as inflammatory bowel disease [4] and obesity [5–7]. Initial studies of the human gut microbiome involved sequencing of the 16S ribosomal RNA gene to determine the main constituents of the community. Although many organisms observed in these studies were previously uncharacterised [8], members of the phyla Firmicutes and Bacteroidetes comprised over 90% of the population of known bacterial species within the gut [4].

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