, Gilead, Novartis Pharmaceuticals, Merck & Co., Idenix, Janssen, Roche Pharma AG, Vertex Pharmaceuticals Christophe Hezode – Speaking and Teaching: Roche, BMS, MSD, Janssen, abb-vie, Gilead Mitchell BTK inhibition L. Shiffman – Advisory Committees or Review Panels: Merck, Gilead, Boehringer-Ingelheim, Bristol-Myers-Squibb, Abbvie, Janssen;

Consulting: Roche/ Genentech, Gen-Probe; Grant/Research Support: Merck, Gilead, Boehring-er-Ingelheim, Bristol-Myers-Squibb, GSK, Abbvie, Beckman-Coulter, Achillion, Lumena, Intercept, Novarit, Gen-Probe; Speaking and Teaching: Roche/Genen-tech, Merck, Gilead, GSK, Janssen, Bayer Stanislas Pol – Board Membership: Sanofi, Bristol-Myers-Squibb, Boehringer Ingelheim, Tibotec Janssen Cilag, Gilead, Glaxo Smith Kline, Roche, MSD, Novartis; Grant/Research Support: Glaxo Smith Kline, Gilead, Roche, MSD; Speaking and Teaching: Sanofi, Bristol-Myers-Squibb, Boehringer Ingelheim, Tibotec Janssen Cilag, Gilead, Glaxo Smith Kline, Roche, MSD, Novartis Marina Berenguer – Advisory Committees or Review Panels: Novartis, Astellas, Janssen, BMS Michael W. Fried – Consulting: Roche/Genentech, Janssen, Vertex, Merck, Bristol Myers Squibb, AbbVie, Merck, GlaxoSmithKline, Gilead; Grant/Research Support: Roche/Genentech, Janssen, Vertex, Merck, Bristol Myers Squibb, AbbVie, NSC 683864 purchase Merck, Gilead Kosh Agarwal -

Advisory Committees or Review Panels: Gilead, Novartis, Abbott; Grant/Research find more Support: Roche, MSD; Speaking and Teaching: BMS, Astellas, Janssen Kris V. Kowdley – Advisory Committees or Review Panels: AbbVie, Gilead, Merck, Novartis, Trio Health,

Boeringer Ingelheim, Ikaria, Janssen; Grant/Research Support: AbbVie, Beckman, Boeringer Ingelheim, BMS, Gilead Sciences, Ikaria, Janssen, Merck, Mochida, Vertex Sandra S. Lovell – Employment: AbbVie Manal Abunimeh – Employment: AbbVie Barbara H. McGovern – Employment: AbbVie The following people have nothing to disclose: Roger Trinh, Antonio Craxi “
“Over the last decade a group of “autoinflammatory disorders” has emerged that reflects genetic defects in the innate immune system leading to spontaneous inflammation. A subgroup of these disorders, the “hereditary recurrent fevers,” ischaracterized by episodes of fevers, serositis, myalgia, arthralgia, rashes, and lymphadenopathy. In this chapter familial Mediterranean fever, TNF receptor-associated periodic syndrome and hyperimmunoglobulinemia D syndrome will be discussed, as these may present to the gastroenterologist. Recognition of clinical presentation will help diagnose such patients and allow correct treatment with potential to reduce risk of amyloidosis. “
“Aim:  To elucidate the etiologic factors and features of liver injury in patients with acute ischemic brain stroke who were treated with edaravone and reported by their attending physicians to have developed serious liver injury.