Future research should incorporate other outcome measures which are more appropriate for cost-effectiveness evaluations in elderly patients,

see more such as functional limitations, and other outcome parameters relevant for the elderly. Furthermore, effectiveness evaluations should be accompanied with economic and cost-effectiveness evaluations. Acknowledgements The authors would like to thank José Breedveld-Peters, Angela Hendrikx, Marionne Vaessen, Nicole Wijckmans-Duysens, Conny de Zwart, Jolanda Nelissen-Braeken and Brigitte Winants for their assistance in data acquisition and entry. We would like to thank André Ament for his assistance during the cost analyses. Furthermore, we would like to thank the dieticians, nurses, trauma and orthopedic surgeons, and other staff members of: Maastricht

University Medical Centre (Maastricht, The Netherlands), Atrium Medical Centre (Heerlen, The Netherlands) and Orbis Medical Centre (Sittard, The Netherlands). Funding This study was funded by The Netherlands Organization for Health Research and Development (ZonMw 80-007022-98-07510). Oral nutritional supplements were kindly provided by Nutricia Advanced Medical Nutrition (Danone Research, Centre for Specialized Nutrition, Wageningen, The Netherlands). Conflicts of interest None. Open Access This article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) AZD9291 supplier CYTH4 and the source are credited. References 1. Cummings SR (1996) Treatable and untreatable risk factors for hip fracture. Bone 18:165S–167SPubMedCrossRef 2. Foster MR, Heppenstall RB, Friedenberg ZB, Hozack WJ (1990) A prospective assessment of nutritional status and complications in patients with fractures of the hip. J Orthop Trauma 4:49–57PubMedCrossRef 3. de Laet CE, van Hout BA, Hofman A, Pols HA (1996) Costs due to osteoporosis-induced fractures in The Netherlands; possibilities for cost control.

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