(C)RSNA, 2011″
“When aptamers first emerged almost two decades ago, most were RNA species that bound and tagged or inhibited simple target ligands. Very soon after, the ‘selectionologists’ developing aptamer technology quickly realized more potential for the aptamer. In recent eFT508 years, advances in aptamer techniques have enabled the use of aptamers as small molecule inhibitors, diagnostic tools and even therapeutics. Aptamers are now being employed in novel applications. We review, herein, some of the recent and exciting applications of aptamers in cell-specific recognition and delivery.”
“In this study, the wear (Akron
and DIN) and the cutting and chipping (C&C) behaviors of hydrogenated nitrile butadiene rubber (HNBR) reinforced by carbon black (N115) and in-situ prepared zinc dimethacrylate (ZDMA) were investigated. It was validated that ZDMA was more effective than N115 to enhance the wear and C&C resistance of HNBR composites. The Akron wear resistance of the HNBR/N115 composites increased with the content of ZDMA, and the Schallamach ridges observed
on the abraded surfaces became less and less clear. With increasing content of ZDMA, the failure mode of the DIN abraded surface underwent the transition from craters buy ABT-263 to Schallamach ridges, and finally to scratches. The HNBR/N115 composite reinforced by 10 phr ZDMA had the best DIN wear resistance when Schallamach ridges were the dominant failure mode. The use of 30 phr ZDMA can dramatically enhance the C&C resistance of the HNBR/N115 composites. The C&C resistance was suggested to be related to both the variation of the morphology of DMXAA solubility dmso the C&C ridges and the direction
of crack propagation as a function of the content of ZDMA. (c) 2011 Wiley Periodicals, Inc. J Appl Polym Sci, 2011″
“Study Design. Retrospective consecutive cohort study.
Objective. To study the effectiveness of beta-tricalcium phosphate (beta-TCP) granules as a packing material in the titanium cages for anterior cervical discectomy and fusion (ACDF), compared with the conventional hydroxyapatite (HA) granules.
Summary of Background Data. ACDF using titanium cages is a standard procedure for the treatment of cervical spinal degenerative diseases. Synthetic bone substitutes are widely used to pack the titanium cage to augment intervertebral bony fusion, but the efficacy has not been confirmed.
Methods. Fusion condition was evaluated on lateral radiographs and computed tomography. Complete fusion of the treated segments was defined by three criteria: movement of the spinous process at flexion and extension positions of less than 3 mm, bony bridging between vertebral bodies, and absence of the halo around the titanium cage. The evaluation was performed at 6 months, 1 year, and 2 years after surgery.
Results.