BMC Med Inform Decis Mak. 2012;12:34.PubMedCrossRef 13. Cooper BS, Medley GF, Stone SP, et al. find more methicillin-resistant Staphylococcus aureus in hospitals and the community: stealth

dynamics and control catastrophes. Proc Natl Acad Sci USA. 2004;101:10223–8.PubMedCrossRef 14. Bootsma MC, Diekmann O, Bonten MJ. Controlling methicillin-resistant Staphylococcus 4-Hydroxytamoxifen aureus: quantifying the effects of interventions and rapid diagnostic testing. Proc Natl Acad Sci USA. 2006;103:5620–5.PubMedCrossRef 15. Robicsek A, Beaumont JL, Thomson RB Jr, Govindarajan G, Peterson LR. Topical therapy for methicillin-resistant Staphylococcus aureus colonization: impact on infection risk. Infect Control Hosp Epidemiol. 2009;30:623–32.PubMedCrossRef 16. Bradley SF. Eradication or decolonization of methicillin-resistant Staphylococcus aureus carriage: what are we doing and why are we doing it? Clin Infect Dis. 2007;44:186–9.PubMedCrossRef 17. Mody L, Kauffman CA, McNeil SA, Galecki AT, Bradley EPZ5676 purchase SF. Mupirocin-based decolonization of Staphylococcus aureus carriers in residents of 2 long-term care facilities: a randomized, double-blind, placebo-controlled trial. Clin Infect Dis. 2003;37:1467–74.PubMedCrossRef 18. Simor AE, Phillips E, McGeer A, et al. Randomized controlled trial of chlorhexidine gluconate for washing, intranasal mupirocin,

and rifampin and doxycycline versus no treatment for the eradication of methicillin-resistant Staphylococcus aureus colonization. Clin Infect Dis. 2007;44:178–85.PubMedCrossRef 19. Diekema D, Johannsson B, Herwaldt L, et al. Current practice in Staphylococcus aureus screening and decolonization. Infect Control Hosp Epidemiol. 2011;32:1042–4.PubMedCrossRef 20. Hernan MA, Hernandez-Diaz S, Robins JM. A structural approach to selection bias. Epidemiology. 2004;15:615–25.PubMedCrossRef 21. Batra R, Cooper

BS, Whiteley C, Patel AK, Wyncoll D, Edgeworth JD. selleck chemical Efficacy and limitation of a chlorhexidine-based decolonization strategy in preventing transmission of methicillin-resistant Staphylococcus aureus in an intensive care unit. Clin Infect Dis. 2010;50:210–7.PubMedCrossRef 22. Coates T, Bax R, Coates A. Nasal decolonization of Staphylococcus aureus with mupirocin: strengths, weaknesses and future prospects. J Antimicrob Chemother. 2009;64:9–15.PubMedCrossRef 23. Lucet JC, Regnier B. Screening and decolonization: does methicillin-susceptible Staphylococcus aureus hold lessons for methicillin-resistant S. aureus? Clin Infect Dis. 2010;51:585–90.PubMedCrossRef”
“Introduction Alcohol related deaths are an important health concern worldwide. In the UK 85% of such deaths are due to cirrhosis and recent epidemiological studies have shown that although mortality rates from cirrhosis are falling in most countries absolute rates remain high, and in the UK and Eastern Europe the trend is upwards with 18% rise in deaths from alcohol related causes between 2000 and 2004 [1–5].