Methods A multi-stage random sampling method had been used to select the investigation items. Univariate analysis and logistic regression model were used to explore the effect of social capital on well being among the old and senior rural-to-urban urbanized residents. Outcomes The results of self-rated real health insurance and psychological state when you look at the rural-to-urban residents were lower than those of metropolitan residents ( P less then 0.05). The sum total rating of neighborhood social capital, neighborhood involvement and community cohesion into the rural-to-urban residents had been less than those of urban residents ( P less then 0.05). The consequence of multivariate evaluation showed that community accessory and community cohesion had been the safety facets of real health ( P less then 0.05), and community cohesion was the safety factor of psychological state ( P less then 0.05). Conclusion There is a correlation between neighborhood belonging, neighborhood cohesion and lifestyle among the list of senior rural-to-urban residents. Attention should really be paid to your promotion of community social capital to be able to improve the health standing of old and senior rural-to-urban residents. Copyright© by Editorial Board of Journal of Sichuan University (Medical Science Edition).Objective This research had been made to explore Periprosthetic joint infection (PJI) the effects of low focus hydrogen inhalation on symptoms of asthma and rest function in mice together with possible mechanism. Methods In the asthma experiment, BALB/c mice were arbitrarily divided into typical control team, asthma design team and hydrogen therapy team. After establishing ovalbumin (OVA)-induced asthma model, the hydrogen treatment group mice had been addressed by breathing of hydrogen (24-26 mL/L per day) for 7 successive times, in addition to normal control group and asthma design team mice obtained comparable therapy by inhalation of air. The amount of interleukin (IL)-4, IL-13, and interferon-γ (IFN-γ) in bronchoalveolar lavage fluid (BALF) were calculated by commercially readily available ELISA kits. The levels of malondialdehyde (MDA) and glutathione (GSH), along with the activity medical level of superoxide dismutase (SOD) in lung structure had been recognized by colorimetric assays. The pathological changes in lung structure were assessed by HE staining. In the sleep research, ICR mice were arbitrarily split into blank control group and 1 d, 3 d, 5 d hydrogen treatment groups and diazepam team. The effects of inhalation of 24-26 mL/L per day hydrogen regarding the sleep duration induced by intraperitoneal injection of upper-threshold dosage of sodium pentobarbital therefore the sleep latency as a result to subthreshold dosage had been evaluated. Leads to the symptoms of asthma research, the symptoms of asthma model team showed greater amounts of IL-4 and IL-13 ( P0.05), that was notably lower than compared to the diazepam group ( P less then 0.05). Conclusion Low concentration hydrogen breathing could relieve OVA-induced symptoms of asthma in mice, in addition to process could be linked to the anti-oxidative and anti-inflammatory results of hydrogen. Also, reasonable focus hydrogen breathing could improve rest purpose in mice. Copyright© by Editorial Board of Journal of Sichuan University (Medical Science Edition).Objective This research was aimed to assess components fundamental constant training induced atrial fibrillation (AF) in an animal design. Methods Healthy brand new Zealand rabbits were divided into three teams ( n=12 each) control team (C), moderate strength group (M), and high intensity group (H). The intensity of constant training buy PND-1186 had been modified based on the treadmill rate. After 12 weeks of training, with a Langendorff perfusion system, AF had been caused by S1S2 stimulation additionally the occurrence had been recorded. Changes in atrial kir2.1, kir2.2, type Ⅰ and Ⅲ collagen protein mRNA expressions had been assessed by quantitative real-time PCR. Masson staining ended up being made use of to evaluate the extracellular collagen volume fraction (CVF) . Results After 12 months, researching with team C, groups M and H had greater ( P less then 0.05) CVF, incidence of AF ( P less then 0.05, also between Groups H and M), and atrial inward rectifier potassium current/channel (IK 1) . In Group H, kir2.1, kir2.2, type Ⅰ and Ⅲ collagen protein mRNA expressions in the left atrium had been increased ( P less then 0.05, compared with Groups C and M). Conclusion long-lasting and high-intensity treadmill working could boost AF incidence in rabbits. Copyright© by Editorial Board of Journal of Sichuan University (Medical Science Edition).Objective to see or watch the changes of cardiac purpose in arthritic rats and the effectation of triptolide about it. Practices Forty rats were split in random into typical control (NC) group, model control (MC) group, leflunomide (LEF) team and triptolide (TP) group. Aside from the normal group, rats when you look at the other three groups had been injected with Freund’s total adjuvant to create arthritic swelling when you look at the right hind paws, plus the interventional medication had been administered from the twelfth time following the inflammation. By managing for 30 d, the cardiac function of rats was detected by left ventricular catheterization. The expressions of superoxide dismutase (SOD), malondialdehyde (MDA), reacitve oxygen species (ROS), total antioxidation (T-AOC), interleukin-10 (IL-10) and tumor necrosis factor-α (TNF-α) in serum had been calculated by enzyme-linked immunosorbent assay. The expressions of keap-like protein 1 ( Keap1), muscular aponeurotic fibrosarcom ( maf) and atomic factor-E2 relevant factor2 ( Nrf2) mRNAs in cardiac tissue had been dets and proteins within the heart tissues of the triptolide group had been diminished ( P less then 0.01). Conclusion Triptolide could enhance cardiac purpose in arthritic rats, plus the mechanism may linked to its ability of improving the anti-oxidationin cardiomyocytes, lowering oxidative tension damage, and suppressing abnormal protected inflammatory response.